Seminar #69: Evolution and analysis of minimal neural circuits for klinotaxis in C. elegans (via Life & Mind seminars)

Currently preparing for this. Next Tuesday (31st Aug., 3:30pm in Arun-401) we will have a special seminar by one of our L&M alumni, Dr. Eduardo Izquierdo. He will give a presentation of his recent work on the topic of: Evolution and analysis of minimal neural circuits for klinotaxis in C. elegans Eduardo Izquierdo Chemotaxis during … Continue reading Seminar #69: Evolution and analysis of minimal neural circuits for klinotaxis in C. elegans (via Life & Mind seminars)

Evolution and analysis of minimal neural circuits for klinotaxis in C. elegans

Paper accepted to the Journal of Neuroscience. Abstract: Chemotaxis during sinusoidal locomotion in nematodes captures in simplified form the general problem of how dynamical interactions between the nervous system, body, and environment are exploited in the generation of adaptive behavior. We used an evolutionary algorithm to generate neural networks that exhibit klinotaxis, a common form … Continue reading Evolution and analysis of minimal neural circuits for klinotaxis in C. elegans

How do you gauge the importance of (data-driven) models?

Imagine you are the editor of two journals, one with higher impact than the other.  You receive two modeling papers, one with more predictions than validations and vice-versa.  You can only accept one to each journal. Where would you send each? What I’m asking is:  How do you gauge the importance of a data-driven* model? … Continue reading How do you gauge the importance of (data-driven) models?

Kandel’s 11 open (and mostly vague) problems in the biology of memory

The Journal of Neuroscience published a series of articles commemorating the 40th anniversary of the society for neuroscience. In an attempt to follow the footsteps of mathematicians, nobel laureate Eric Kandel proposed 11 open problems for the future of understanding memory: 1. How does synaptic growth occur, and how is signaling across the synapse coordinated … Continue reading Kandel’s 11 open (and mostly vague) problems in the biology of memory

Recommended reading

Abbott, L.F. (2008) Theoretical Neuroscience Rising. Neuron 60:489-495. Key passages from my favorite parts of the paper: “Neuroscience has always had models, but prior to the invasion of the theorists, these were often word models. Equations force a model to be precise, complete, and self-consistent, and they allow its full implications to be worked out.” … Continue reading Recommended reading